Histamine is a major cause of migraines. Histamine increases nitric oxide, which causes vasodilation (ie expansion) of blood vessels. Vasodilation increases blood flow to the brain. The nervous system responds to this increased blood flow with symptoms of pain, flashing lights, double vision, vertigo, increased sensitivity to light, smells and noise as well as nausea, vomiting and diarrhoea.
Histamine contributes to the pain and inflammation in bladder conditions including painful bladder syndrome / interstitial cystitis (PBS/IC). Reducing your histamine load can provide significant relief of symptoms.
Histamine is a major cause of eczema. Reducing your histamine load by treating the gut, detoxifying oestrogen and reducing high histamine foods can provide significant relief of eczema.